Increased Immunogenicity and Protective Efficacy of Influenza M2e Fused to a Tetramerizing Protein
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منابع مشابه
Increased Immunogenicity and Protective Efficacy of Influenza M2e Fused to a Tetramerizing Protein
The ectodomain of the matrix 2 protein (M2e) of influenza A virus represents an attractive target for developing a universal influenza A vaccine, with its sequence being highly conserved amongst human variants of this virus. With the aim of targeting conformational epitopes presumably shared by diverse influenza A viruses, a vaccine (M2e-NSP4) was constructed linking M2e (in its consensus seque...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0046395